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OSGear Team
Pro-Tesofensine (Extra) - Beligas
ACTIVE HALF-LIFE 9 days
CLASSIFICATION Psychoactive Antidepressants (SNDRI)
DOSAGE 0.25 mg - 1 mg
ACNE No
WATER RETENTION No
HBR Perhaps
HEPATOTOXICITY Low
AROMATIZATION No
MANUFACTURER Beligas
WAREHOUSE International Warehouse 3
SUBSTANCE
Tesofensine,
⁃ act centrally, suppress appetite, regulate the availability of dopamine receptors and stimulate α1-adrenergic receptors.
⁃ appetite decreases within 14 days, there is a higher level of satiety and less desire to eat.
⁃ increases significantly fat oxidation and reduces adipose tissue.
⁃ improves the level of insulin sensitivity, which leads to higher glucose metabolism.
⁃ alters the expression of dopaminergic receptors in the striatum of the brain, as well as their binding.
⁃ the energy consumption increases greatly within 14 days.
⁃ the drug has a long half-life, which is 8-9 days, and metabolized mainly in the liver by CYP3A4 to the disalkyl metabolite M1 (NS-2360), which is the only metabolite found in human blood plasma.